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University of Minnesota

Institute of Technology

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Claudia Schmidt-Dannert

Associate Professor, Biochemistry, Molecular Biology and Biophysics
Office: 274 Gortner Lab
Phone: 612-625-5782
Email: schmi232@umn.edu
Departmental Page

Professional Preparation:

Technical University of Braunschweig, Germany Biology B. Sc. 1988
Technical University of Braunschweig, Germany Biochemistry M. Sc. 1991
Technical University of Braunschweig, Germany Biochemistry Ph. D. 1994
University of Stuttgart, Germany Biotechnology Postdoc 1994-1995

Professional Appointments

2005-present Associate Professor of Biochemistry, Molecular Biology. Biophysics, UMN
2000-2005 Assistant Professor of Biochemistry, Molecular Biology, Biophysics, UMN
1998-2000 Postdoc (Habilitation Fellowship), Dept. Chem. Eng., Caltech (with Frances Arnold)
1995-1998 Head Molecular Biotechnology Group, Technical Biochemistry, U Stuttgart
1992-1994 Ph.D. Research Assistant, National Research Center for Biotechnology (GBF), Braunschweig, Germany


Selected Publications

K.T. Watts, B.N. Mijts, P.C. Lee, A. J. Manning and C. Schmidt-Dannert (2006) Discovery of a substrateselectivity switch in tyrosine ammonia lyase: a new member of the aromatic amino acid lyase family. Chem. Biol. 13:1317-1326 (cover)

K.T. Watts, P.C. Lee and C. Schmidt-Dannert (2006) Biosynthesis of plant specific stilbene polyketides in metabolically engineered E. coli. BMC Biotechnol. 6:22

B. Mijts, P.C. Lee and C. Schmidt-Dannert (2005) Identification of a carotenoid oxygenase synthesizing novel acyclic carotenoids: combinatorial biosynthesis and directed evolution. Chem. Biol. 12:1-8

K. Watts, P.C. Lee, C. Schmidt-Dannert (2004) Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli. ChemBioChem. 5:500-507.

P.C. Lee, A.Z.R. Momen, B. Mijts, C. Schmidt-Dannert (2003) Biosynthesis of structurally novel carotenoids in Escherichia coli. Chem. Biol. 10:452-463.

P.C. Lee, C. Salomon, B. Mijts and C. Schmidt-Dannert (2008) Biosynthesis of ubiquinones with conjugated prenyl side chains. Appl. Environ. Microbiol. Appl. Environ. Microbiol. 74:6908-17

S. Agger, F. Lopez-Gallego, T.R. Hoye and C. Schmidt-Dannert (2008) Identification of Sesquiterpene Synthases from Nostoc punctiforme PCC 73102 and Nostoc sp PCC 7120. J. Bacteriol. 190(18):6084-96.

E.T. Johnson and C. Schmidt-Dannert (2008) Characterization of three homologs of the large subunit of the magnesium chelatase from Chlorobium tepidum and interaction with the magnesium protoporphyrin IX methyltransferase. J. Biol. Chem. 283:27776-84

E. Marasco and C. Schmidt-Dannert (2008) Identification of bacterial carotenoid cleavage dioxygenase homologs that cleave the interphenyl α,β double bond of stilbene derivatives via a monooxygenase reaction. ChemBiochem, 9:1450-1461

E. Holtzapple and C. Schmidt-Dannert (2007) Biosynthesis of Isoprenoid Wax Ester in Marinobacter hydrocarbonoclasticus DSM 8798: Identification and Characterization of Isoprenoid Coenzyme A Synthetase and Wax Ester Synthases. J. Bacteriol. 189:3804-12.